About Enhancer
| Enhancer ID: | E_03141 |
| Species: | Mus musculus |
| Position : | chr1:134714823-134715623   |
| Year: | 2017 |
| Title: | Identification of an Enhancer Critical for the ephrin-A5 Gene Expression in the Posterior Region of the Mesencephalon |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 28614915 |
| MONDO: | |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Primary mouse mesencephalic cells |
| CVCL ID: | |
| Cell Type: | neuron |
| Cell Ontology ID: | CL:0000540 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | |
| Low Throughput Method: | Transgenic Reporter Assay, Luciferase Reporter Assay, EMSA |
About Target Gene
| Target gene : | Efna5 |
About TF
| TF name : | Ascl1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Ascl1 | Notch-mediated HES/HEY network | pid | 48 |
| Ascl1 | Notch | netpath | 76 |
| Ascl1 | Hs_Dopaminergic_Neurogenesis_WP2855_87239 | wikipathways | 19 |
| Ascl1 | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer