About Enhancer
| Enhancer ID: | E_03159 |
| Species: | Homo sapiens |
| Position : | chr11:5266021-5266708   |
| Year: | 1999 |
| Title: | Structural and functional cross-talk between a distant enhancer and the epsilon-globin gene promoter shows interdependence of the two elements in chromatin. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 10523648 |
| Tissue: | blood / hematopoietic system |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Experiment Type: | Experimentally supported enhancer study |
| Low Throughput Method: | 3C |
About Target Gene
| Target gene : | HBE1 |
About TF
| TF name : | NFE2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFE2 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
8 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02356 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02363 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02364 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02365 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_04561 | chr11:5264845-5266345 | blood / hematopoietic system | NA | NA |
| E_03158 | chr11:5266021-5266708 | blood / hematopoietic system | NA | NA |
| E_03162 | chr11:5266021-5266708 | blood | erythroid cell | NA |
| E_03163 | chr11:5266021-5266708 | blood | erythroid cell | NA |
Expression of Target Genes for the Enhancer