About Enhancer
| Enhancer ID: | E_03193 |
| Species: | Homo sapiens |
| Position : | chr22:38686443-38686999   |
| Year: | 2022 |
| Title: | B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 35778390 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | B cells |
| Cell Type: | B cell |
| Cell Ontology ID: | CL:0000236 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay; Endogenous enhancer perturbation |
| High Throughput Method: | ATAC-seq, CUT&Tag, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, CRISPRi, qRT-PCR, Western blot; CRISPR-Cas9 endogenous deletion/editing |
About Target Gene
| Target gene : | APOBEC3C |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer