About Enhancer
| Enhancer ID: | E_03212 |
| Species: | Mus musculus |
| Position : | chr6:1778-2113   |
| Year: | 2011 |
| Title: | Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targeting of SHP1 Tyrosine Phosphatase |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | hepatocellular carcinoma |
| PMID: | 20864515 |
| MONDO: | MONDO:0007256 |
| Tissue: | Liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | HepG2 |
| CVCL ID: | CVCL_0027 |
| Cell Type: | hepatocellular carcinoma cell |
| Cell Ontology ID: | CL:0000182 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, Re-ChIP, RT-RT-qPCR, Western blot, Euglycemic Hyperinsulinemic Clamp, Antisense Oligonucleotide Silencing |
About Target Gene
| Target gene : | Ptpn6 |
About TF
| TF name : | Prep1; Pbx1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer