Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03221
Species: Mus musculus
Position : chr1:133452484-133452725
Year: 2014
Title: A mouse renin distal enhancer is essential for blood pressure homeostasis in BAC-rescued renin-null mutant mice
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  24734888
MONDO:
Tissue: Kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: Mouse juxtaglomerular cells
CVCL ID:
Cell Type: juxtaglomerular cell
Cell Ontology ID: CL:0000647
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method:
Low Throughput Method: BAC Transgenic Reporter Assay, Luciferase Reporter Assay, Northern blot, RT-RT-qPCR, Radioimmunoassay, In situ hybridization, Conditional knockout rescue
About Target Gene
Target gene : Ren-1C
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer