Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03237
Species: Mus musculus
Position : chr14:77122986-77124293
Year: 2011
Title: Mouse Rankl Expression Is Regulated in T Cells by c-Fos through a Cluster of Distal Regulatory Enhancers Designated the T Cell Control Region
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Disease
Disease Name: T-cell acute lymphoblastic leukemia
PMID:  21498522
MONDO: MONDO:0004947
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: Jurkat cells
CVCL ID: CVCL_0065
Cell Type: T lymphoblast
Cell Ontology ID: CL:0002419
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method: ChIP-chip
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR
About Target Gene
Target gene : Rankl
About TF
TF name : C-Fos
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_03236 chr14:77122986-77124293 Spleen CD4-positive T cell --
Expression of Target Genes for the Enhancer