About Enhancer
| Enhancer ID: | E_03246 |
| Species: | Mus musculus |
| Position : | chr6:6770399-6771465   |
| Year: | 2011 |
| Title: | Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 20878775 |
| MONDO: | |
| Tissue: | Bone |
| Tissue Ontology ID: | UBERON:0001474 |
| Cell Source: | MC3T3-E1 |
| CVCL ID: | CVCL_0D73 |
| Cell Type: | osteoblast |
| Cell Ontology ID: | CL:0000062 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, GST Pull-down, Co-IP, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | Runx2 |
About TF
| TF name : | Smad1; Smad4; Tcf4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer