Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03248
Species: Mus musculus
Position : chr13:114453916-114454191
Year: 2011
Title: Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  20878775
MONDO:
Tissue: Skeletal muscle
Tissue Ontology ID: UBERON:0001134
Cell Source: C2C12
CVCL ID: CVCL_0188
Cell Type: myoblast
Cell Ontology ID: CL:0000187
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR
About Target Gene
Target gene : Msx2
About TF
TF name : Smad1; Smad4; Tcf4
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_03249 chr13:114453916-114454191 Bone osteoblast --
Expression of Target Genes for the Enhancer