Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03252
Species: Mus musculus
Position : chr17:44819323-44819541
Year: 2011
Title: Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  20878775
MONDO:
Tissue: Bone marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: BM-MSC
CVCL ID:
Cell Type: mesenchymal stem cell
Cell Ontology ID: CL:0000134
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot
About Target Gene
Target gene : Runx2
About TF
TF name : Smad1; Smad4; Tcf4
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_03250 chr17:44819323-44819541 Skeletal muscle myoblast --
E_03251 chr17:44819323-44819541 Bone osteoblast --
Expression of Target Genes for the Enhancer