About Enhancer
| Enhancer ID: | E_03273 |
| Species: | Mus musculus |
| Position : | chr6:71252310-71308680   |
| Year: | 2015 |
| Title: | A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8aa+ dendritic cells |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 25548254 |
| MONDO: | |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Effector memory CD8+ T cells |
| CVCL ID: | |
| Cell Type: | effector memory CD8+ T cell |
| Cell Ontology ID: | CL:0000625 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | |
| Low Throughput Method: | Transgenic Reporter Assay, ChIP-RT-qPCR |
About Target Gene
| Target gene : | Hcd2 |
About TF
| TF name : | Runx3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Runx3 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Runx3 | TGF_beta_Receptor | netpath | 220 |
| Runx3 | Hs_TYROBP_Causal_Network_WP3945_90843 | wikipathways | 54 |
| Runx3 | Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078 | wikipathways | 33 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer