About Enhancer
| Enhancer ID: | E_03286 |
| Species: | Homo sapiens |
| Position : | chr2:176265000-176270000   |
| Year: | 2022 |
| Title: | EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Ewing sarcoma |
| PMID: | 35653119 |
| MONDO: | MONDO:0012817 |
| Tissue: | bone tissue |
| Tissue Ontology ID: | UBERON:0002481 |
| Cell Source: | TC32 |
| Cell Type: | Ewing sarcoma cell |
| Experiment Type: | Enhancer activity assay; TF binding assay; Chromatin interaction assay; Functional perturbation assay |
| High Throughput Method: | ChIP-seq; CUT&RUN; RNA-seq; HiChIP; CITE-seq |
| Low Throughput Method: | ChIP-qPCR; CRISPRi; RT-qPCR; Western blot; Flow cytometry |
About Target Gene
| Target gene : | HOXD13 |
About TF
| TF name : | EWSR1::FLI1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer