Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03301
Species: Mus musculus
Position : chr6:115598005-115604631
Year: 2017
Title: YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  29224777
MONDO:
Tissue: Embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: Embryonic stem cell
CVCL ID:
Cell Type: embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: Chromatin interaction assay, Functional perturbation assay
High Throughput Method: ChIP-seq, Hi-C
Low Throughput Method: CRISPR Knockout, 4C-seq, RT-RT-qPCR
About Target Gene
Target gene : Raf1
About TF
TF name : Yy1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Yy1 Activation of anterior HOX genes in hindbrain development during early embryogenesis reactome 120
Yy1 DNA Damage Recognition in GG-NER reactome 38
Yy1 E2F transcription factor network pid 77
Yy1 mTOR signaling pathway pid 66
Yy1 Notch-mediated HES/HEY network pid 48
Yy1 Notch netpath 76
Yy1 Notch signaling pathway pid 58
Yy1 p53 pathway pid 59
Yy1 Signaling events mediated by HDAC Class I pid 89
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_03300 chr6:115598005-115604631 Embryo mouse embryonic stem cell --
Expression of Target Genes for the Enhancer