About Enhancer
| Enhancer ID: | E_03304 |
| Species: | Mus musculus |
| Position : | chr19:45700000-45702000   |
| Year: | 2017 |
| Title: | Isoform-specific expression and feedback regulation of E protein TCF4 control dendritic cell lineage specification |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 27986456 |
| MONDO: | |
| Tissue: | Bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | Plasmacytoid dendritic cell (pDC) |
| CVCL ID: | |
| Cell Type: | plasmacytoid dendritic cell |
| Cell Ontology ID: | CL:0000786 |
| Experiment Type: | Functional perturbation assay |
| High Throughput Method: | ATAC-seq, ChIP-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR |
About Target Gene
| Target gene : | Tcf4 |
About TF
| TF name : | Tcf4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Tcf4 | AndrogenReceptor | netpath | 167 |
| Tcf4 | CDO in myogenesis | reactome | 29 |
| Tcf4 | Coregulation of Androgen receptor activity | pid | 61 |
| Tcf4 | Formation of the beta-catenin:TCF transactivating complex | reactome | 88 |
| Tcf4 | ID | netpath | 38 |
| Tcf4 | Regulation of nuclear beta catenin signaling and target gene transcription | pid | 80 |
| Tcf4 | TGF_beta_Receptor | netpath | 220 |
| Tcf4 | Wnt | netpath | 118 |
| Tcf4 | Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 | wikipathways | 41 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer