Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03324
Species: Mus musculus
Position : chr11:44203400-44203700
Year: 2011
Title: A distal enhancer in Il12b is the target of transcriptional repression by the STAT3 pathway and requires the basic leucine zipper (B-ZIP) protein NFIL3
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  21566115
MONDO:
Tissue: Bone marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: BMDM
CVCL ID:
Cell Type: macrophage
Cell Ontology ID: CL:0000235
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, EMSA, RT-RT-qPCR
About Target Gene
Target gene : Il12B
About TF
TF name : Nfil3
About Regulatory State
Regulatory State : Silenced
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 4 found
Enhancer ID Position Tissue Cell Disease
E_03138 chr11:44203545-44203644 Bone Marrow macrophage --
E_03328 chr11:44203545-44203644 Bone marrow macrophage --
E_03329 chr11:44203545-44203644 Bone marrow macrophage --
E_03330 chr11:44203545-44203644 Bone marrow macrophage --
Expression of Target Genes for the Enhancer