About Enhancer
| Enhancer ID: | E_03337 |
| Species: | Homo sapiens |
| Position : | chr17:64082103-64082506   |
| Year: | 2022 |
| Title: | FOXK2 promotes ovarian cancer stemness by regulating the unfolded protein response pathway. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | ovarian carcinoma |
| PMID: | 35349489 |
| MONDO: | MONDO:0005140 |
| Tissue: | ovary |
| Tissue Ontology ID: | UBERON:0000992 |
| Cell Source: | OVCAR-5 |
| CVCL ID: | CVCL_1628 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay; Endogenous enhancer perturbation; TF binding assay |
| High Throughput Method: | ChIP-seq, RNA-seq, ATAC-seq |
| Low Throughput Method: | ChIP-RT-qPCR, CRISPR-dCas9, qRT-PCR, Western blot; CRISPR-Cas9 endogenous deletion/editing; ChIP |
About Target Gene
| Target gene : | ERN1 |
About TF
| TF name : | FOXK2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer