About Enhancer
| Enhancer ID: | E_03341 |
| Species: | Homo sapiens |
| Position : | chr7:87574094-87575396   |
| Year: | 2020 |
| Title: | A stress-responsive enhancer induces dynamic drug resistance in acute myeloid leukemia. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | acute myeloid leukemia |
| PMID: | 31770110 |
| MONDO: | MONDO:0018874 |
| Tissue: | bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | Primary AML blasts |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Functional perturbation assay, TF binding assay, Enhancer activity assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, RNA-seq, 4C-seq |
| Low Throughput Method: | CRISPRi, ChIP-RT-qPCR, RT-RT-qPCR, Flow Cytometry |
About Target Gene
| Target gene : | ABCB1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer