About Enhancer
| Enhancer ID: | E_03363 |
| Species: | Mus musculus |
| Position : | chr11:96880000-96920000   |
| Year: | 2018 |
| Title: | Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 29514092 |
| MONDO: | |
| Tissue: | Bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | Non-classical monocytes |
| CVCL ID: | |
| Cell Type: | non-classical monocyte |
| Cell Ontology ID: | CL:0000576 |
| Experiment Type: | Immunological functional assay, Functional genomics assay, Epigenomic profiling assay, Transcriptional regulation assay |
| High Throughput Method: | ChIP-seq [targets: H3K4me1, H3K27ac, Irf8], RNA-seq, Gene Expression Microarray |
| Low Throughput Method: | Flow Cytometry, FACS, qRT-PCR, ChIP-RT-qPCR, Western blot, Immunofluorescence Microscopy |
About Target Gene
| Target gene : | Nr4A1 |
About TF
| TF name : | Irf8; Spi1; Klf2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02812 | chr11:96883943-96888120 | Hindbrain | -- | -- |
Expression of Target Genes for the Enhancer