About Enhancer
| Enhancer ID: | E_03364 |
| Species: | Homo sapiens |
| Position : | chr18:60793273-60794103   |
| Year: | 2015 |
| Title: | SATB1 Mediates Long-Range Chromatin Interactions: A Dual Regulator of Anti-Apoptotic BCL2 and Pro-Apoptotic NOXA Genes. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26422397 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Jurkat |
| CVCL ID: | CVCL_0065 |
| Cell Type: | T cell |
| Cell Ontology ID: | CL:0000084 |
| Experiment Type: | TF binding assay; Chromatin interaction assay; Functional perturbation assay |
| Low Throughput Method: | 3C-qPCR; SATB1 ChIP-qPCR; SATB1 shRNA knockdown; RT-qPCR; Western blot; Caspase-6 perturbation; 3C-product sequencing; 3C |
About Target Gene
| Target gene : | PMAIP1 |
About TF
| TF name : | SATB1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| SATB1 | Apoptotic cleavage of cellular proteins | reactome | 18 |
| SATB1 | Caspase Cascade in Apoptosis | pid | 57 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03363 | chr18:60793273-60794103 | blood | T cell | NA |
Expression of Target Genes for the Enhancer