Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03385
Species: Homo sapiens
Position : chr6:31130000-31131000
Year: 2022
Title: Systematic comparison of CRISPR-based transcriptional activators uncovers gene-regulatory features of enhancer-promoter interactions.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
PMID:  35849129
Tissue: kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: HEK293
CVCL ID: CVCL_0045
Cell Type: embryonic kidney cell
Experiment Type: Functional perturbation assay
Low Throughput Method: CRISPR Knockout; CRISPRi; RT-RT-qPCR
About Target Gene
Target gene : POU5F1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 2 found
Enhancer ID Position Tissue Cell Disease
E_03380 chr6:31130000-31131000 uterine cervix malignant cell cervical cancer
E_03381 chr6:31130000-31131000 blood malignant cell chronic myeloid leukemia
Expression of Target Genes for the Enhancer