Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03388
Species: Homo sapiens
Position : chr5:148781015-148839604
Year: 2015
Title: CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis.
Genome Build: hg19
Enhancer Type: Super-enhancer
Condition: Normal
PMID:  26423156
Tissue: heart
Tissue Ontology ID: UBERON:0000948
Cell Source: Human fetal cardiac precursor cells
Cell Type: cardiac progenitor cell
Experiment Type: Super-enhancer profiling; Functional perturbation assay; lncRNA regulatory assay
High Throughput Method: RNA-seq; Super-enhancer chromatin-state profiling
Low Throughput Method: GapmeR-mediated CARMN knockdown; RT-qPCR; RNA immunoprecipitation; SUZ12/EZH2 interaction assay; Cardiac differentiation assay
About Target Gene
Target gene : CARMN
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 1 found
Enhancer ID Position Tissue Cell Disease
E_03346 chr5:148785000-148815000 heart NA NA
Expression of Target Genes for the Enhancer