About Enhancer
| Enhancer ID: | E_03389 |
| Species: | Mus musculus |
| Position : | chr1:154149500-154150000   |
| Year: | 2024 |
| Title: | A transcriptional enhancer regulates cardiac maturation |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 39196225 |
| MONDO: | |
| Tissue: | Heart |
| Tissue Ontology ID: | UBERON:0000948 |
| Cell Source: | Mouse embryonic/Adult cardiomyocytes |
| CVCL ID: | |
| Cell Type: | cardiomyocyte |
| Cell Ontology ID: | CL:0000746 |
| Experiment Type: | TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | ChIP-RT-qPCR, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | Actn2 |
About TF
| TF name : | Mef2A |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Mef2A | CDO in myogenesis | reactome | 29 |
| Mef2A | ERK/MAPK targets | reactome | 17 |
| Mef2A | Signaling mediated by p38-alpha and p38-beta | pid | 35 |
| Mef2A | TGF_beta_Receptor | netpath | 220 |
| Mef2A | Hs_p38_MAPK_Signaling_Pathway_WP400_72084 | wikipathways | 28 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02469 | chr1:154150000-154150500 | Heart | cardiomyocyte | -- |
Expression of Target Genes for the Enhancer