About Enhancer
| Enhancer ID: | E_03413 |
| Species: | Homo sapiens |
| Position : | chr2:44294900-44295100   |
| Year: | 2024 |
| Title: | The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | neuroblastoma |
| PMID: | 38992040 |
| MONDO: | MONDO:0005072 |
| Tissue: | adrenal gland |
| Tissue Ontology ID: | UBERON:0002369 |
| Cell Source: | Kelly |
| CVCL ID: | CVCL_2092 |
| Cell Type: | neuroblastoma cell |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq; RNA-seq; ATAC-seq |
| Low Throughput Method: | ChIP-RT-qPCR; CRISPR Knockout, qRT-PCR; Western blot |
About Target Gene
| Target gene : | NTRK1 |
About TF
| TF name : | HAND2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| HAND2 | Hs_Heart_Development_WP1591_90186 | wikipathways | 28 |
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer