About Enhancer
| Enhancer ID: | E_03415 |
| Species: | Homo sapiens |
| Position : | chr6:31137269-31137697   |
| Year: | 2018 |
| Title: | TFAP2C regulates transcription in human naive pluripotency by opening enhancers. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 29695788 |
| Cell Source: | Embryonic Stem Cell |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Endogenous enhancer perturbation |
| High Throughput Method: | ChIP-seq; ATAC-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP |
About Target Gene
| Target gene : | POU5F1 |
About TF
| TF name : | TFAP2C |
About Regulatory State
| Regulatory State : | Repressed |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TFAP2C | Validated transcriptional targets of TAp63 isoforms | pid | 54 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01748 | chr6:31137056-31138028 | NA | NA | NA |
Expression of Target Genes for the Enhancer