About Enhancer
| Enhancer ID: | E_03417 |
| Species: | Homo sapiens |
| Position : | chr6:34223538-34224727   |
| Year: | 2024 |
| Title: | Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 39294132 |
| Tissue: | pleural effusion |
| Tissue Ontology ID: | UBERON:0000175 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activation assay; Functional perturbation assay; Endogenous enhancer perturbation |
| High Throughput Method: | Multiplex single-cell CRISPRa screen; scRNA-seq; singleton bulk RNA-seq validation; external ENCODE ATAC-seq; external ENCODE H3K27ac ChIP-seq; single-cell RNA-seq; RNA-seq; pooled CRISPRa screen; CRISPR genetic screen |
| Low Throughput Method: | Singleton CRISPRa perturbation; CRISPRa |
About Target Gene
| Target gene : | HMGA1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer