About Enhancer
| Enhancer ID: | E_03418 |
| Species: | Mus musculus |
| Position : | chr4:95630001-95639906   |
| Year: | 2020 |
| Title: | The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 32647123 |
| Tissue: | cerebellum |
| Tissue Ontology ID: | UBERON:0002037 |
| Cell Source: | Cerebellar granule neurons |
| Cell Type: | cerebellar granule neuron |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Hi-C; ChIP-seq; DNaseI-seq; RNA-seq |
| Low Throughput Method: | RT-RT-qPCR; Western blot |
About Target Gene
| Target gene : | Jun |
About TF
| TF name : | Chd4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Chd4 | Activation of rRNA Expression by ERCC6 (CSB) and EHMT2 (G9a) | reactome | 74 |
| Chd4 | HDACs deacetylate histones | reactome | 94 |
| Chd4 | Regulation of TP53 Activity through Acetylation | reactome | 23 |
| Chd4 | RNA Polymerase I Transcription Initiation | reactome | 47 |
| Chd4 | Signaling events mediated by HDAC Class I | pid | 89 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03419 | chr4:95630001-95639906 | cerebellum | cerebellar granule neuron | NA |
Expression of Target Genes for the Enhancer