About Enhancer
| Enhancer ID: | E_03419 |
| Species: | Mus musculus |
| Position : | chr4:95630001-95639906   |
| Year: | 2020 |
| Title: | The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 32647123 |
| Tissue: | cerebellum |
| Tissue Ontology ID: | UBERON:0002037 |
| Cell Source: | Cerebellar granule neurons |
| Cell Type: | cerebellar granule neuron |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Hi-C; ChIP-seq; DNaseI-seq; RNA-seq |
| Low Throughput Method: | RT-RT-qPCR; Western blot |
About Target Gene
| Target gene : | Jun |
About TF
| TF name : | Smc1a |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Smc1a | ATM pathway | pid | 34 |
| Smc1a | Cohesin Loading onto Chromatin | reactome | 10 |
| Smc1a | Establishment of Sister Chromatid Cohesion | reactome | 11 |
| Smc1a | Meiotic synapsis | reactome | 76 |
| Smc1a | Resolution of Sister Chromatid Cohesion | reactome | 100 |
| Smc1a | Separation of Sister Chromatids | reactome | 163 |
| Smc1a | SUMOylation of DNA damage response and repair proteins | reactome | 76 |
| Smc1a | Cell cycle | kegg | 124 |
| Smc1a | Cell cycle - yeast | kegg | 66 |
| Smc1a | Meiosis - yeast | kegg | 58 |
| Smc1a | Oocyte meiosis | kegg | 110 |
| Smc1a | Hs_DNA_Damage_Response_WP707_82937 | wikipathways | 28 |
| Smc1a | Hs_miRNA_Regulation_of_DNA_Damage_Response_WP1530_84694 | wikipathways | 28 |
| Smc1a | Hs_ATM_Signaling_Pathway_WP2516_90247 | wikipathways | 32 |
| Smc1a | Hs_DNA_IR-Double_Strand_Breaks_(DSBs)_and_cellular_response_via_ATM_WP3959_91367 | wikipathways | 50 |
| Smc1a | Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271 | wikipathways | 27 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03418 | chr4:95630001-95639906 | cerebellum | cerebellar granule neuron | NA |
Expression of Target Genes for the Enhancer