About Enhancer
| Enhancer ID: | E_03424 |
| Species: | Mus musculus |
| Position : | chr18:61108475-61108975   |
| Year: | 2011 |
| Title: | Differential regulation of sense and antisense promoter activity at the Csf1R locus in B cells by the transcription factor PAX5. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 21549805 |
| Tissue: | bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | primary B220+ bone marrow B cells |
| Cell Type: | B cell |
| Cell Ontology ID: | CL:0000236 |
| Experiment Type: | Enhancer/antisense-promoter activity assay; TF binding assay; Functional perturbation assay |
| Low Throughput Method: | Luciferase reporter assay; EMSA; oligonucleotide pull-down; Sp3 knockout; RT-qPCR; ChIP |
About Target Gene
| Target gene : | Csf1r |
About TF
| TF name : | Sp3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Sp3 | Leptin | netpath | 98 |
| Sp3 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Sp3 | Regulation of Telomerase | pid | 70 |
| Sp3 | SUMOylation of transcription factors | reactome | 14 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer