Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03463
Species: Homo sapiens
Position : chr16:103290-103957
Year: 2007
Title: Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.
Genome Build: hg18
Enhancer Type: Enhancer
Condition: Normal
PMID:  17715390
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: Primary human erythroblasts
Cell Type: erythroblast
Cell Ontology ID: CL:0000765
Experiment Type: TF binding assay; Chromatin modification assay; In vivo functional validation
High Throughput Method: ChIP-chip
Low Throughput Method: ChIP-qPCR; In vivo phenotyping
About Target Gene
Target gene : HBA2
About TF
TF name : NFE2
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
NFE2 Factors involved in megakaryocyte development and platelet production reactome 111
Enhancer Associated Network
Overlapping Enhancers (hg18) 5 found
Enhancer ID Position Tissue Cell Disease
E_03460 chr16:103290-103957 blood erythroblast NA
E_03461 chr16:103290-103957 blood erythroblast NA
E_03462 chr16:103290-103957 blood erythroblast NA
E_03464 chr16:103290-103957 blood erythroblast NA
E_03465 chr16:103290-103957 blood erythroblast NA
Expression of Target Genes for the Enhancer