Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03472
Species: Homo sapiens
Position : chr10:35949193-35950411
Year: 2025
Title: A human-specific enhancer fine-tunes radial glia potency and corticogenesis
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
PMID:  40369080
Tissue: cerebral cortex
Tissue Ontology ID: UBERON:0000956
Cell Type: radial glial cell
Cell Ontology ID: CL:0000680
Experiment Type: in vivo reporter assay; genome editing
High Throughput Method: RNA-seq; scRNA-seq; ChIP-qPCR; CRISPRi
Low Throughput Method: Immunohistochemistry; luciferase reporter assay; RT-qPCR
About Target Gene
Target gene : FZD8
About TF
TF name : NR
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_01346 chr10:35949493-35950111 Brain radial glial cell --
Expression of Target Genes for the Enhancer