About Enhancer
| Enhancer ID: | E_03476 |
| Species: | Homo sapiens |
| Position : | chr7:117052000-117053500   |
| Year: | 2020 |
| Title: | Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | lung adenocarcinoma |
| PMID: | 32095812 |
| MONDO: | MONDO:0005032 |
| Tissue: | Lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | Calu3 |
| CVCL ID: | CVCL_0609 |
| Cell Type: | lung adenocarcinoma cell |
| Cell Ontology ID: | CL:0001069 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, ATAC-seq, 4C-seq, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Sulforaphane Treatment |
About Target Gene
| Target gene : | CFTR |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03475 | chr7:117052000-117053500 | Airway epithelium | bronchial epithelial cell | -- |
Expression of Target Genes for the Enhancer