Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03477
Species: Homo sapiens
Position : chr10:89986509-89987396
Year: 2023
Title: Landscape of enhancer disruption and functional screen in melanoma cells
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: skin melanoma
PMID:  37904237
MONDO: MONDO:0005105
Tissue: Skin
Tissue Ontology ID: UBERON:0000014
Cell Source: Melanoma cell line
CVCL ID:
Cell Type: melanoma cell
Cell Ontology ID: CL:0002573
Experiment Type: Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method: HiChIP, ATAC-seq, ChIP-seq, RNA-seq
Low Throughput Method: Luciferase Reporter Assay, CRISPR Knockout, CRISPRi, 3C-seq, 4C-seq, RT-RT-qPCR, Western blot
About Target Gene
Target gene : PTEN
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer