About Enhancer
| Enhancer ID: | E_03490 |
| Species: | Homo sapiens |
| Position : | chr9:126770367-126771183   |
| Year: | 2020 |
| Title: | Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | -- |
| PMID: | 32238901 |
| MONDO: | |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | |
| CVCL ID: | |
| Cell Type: | |
| Cell Ontology ID: | |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq, Hi-C, ATAC-seq |
| Low Throughput Method: | Luciferase Reporter Assay, Transgenic Reporter Assay, CRISPR Knockout, CRISPRi, qRT-PCR |
About Target Gene
| Target gene : | LHX2 |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00955 | chr9:126753431-126803431 | Blood | CD34-positive hematopoietic stem cell | -- |
Expression of Target Genes for the Enhancer