About Enhancer
| Enhancer ID: | E_03491 |
| Species: | Homo sapiens |
| Position : | chr20:48900221-48901229   |
| Year: | 2019 |
| Title: | Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 30659195 |
| MONDO: | |
| Tissue: | Liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | Human normal liver cell |
| CVCL ID: | |
| Cell Type: | hepatocyte |
| Cell Ontology ID: | CL:0000182 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | MBDCap-seq, WGBS, ChIP-seq, RNA-seq, Hi-C |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knockout, ChIP-RT-qPCR, RT-RT-qPCR, Western blot, Bisulfite pyrosequencing |
About Target Gene
| Target gene : | CEBPB |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00836 | chr20:48400000-49200000 | Breast | breast carcinoma cell | breast carcinoma |
| E_00837 | chr20:48400000-49200000 | Breast | breast carcinoma cell | breast carcinoma |
| E_00363 | chr20:48900221-48901229 | Liver | hepatocellular carcinoma cell | hepatocellular carcinoma |
| E_03512 | chr20:48900221-48901229 | Liver | hepatocellular carcinoma cell | hepatocellular carcinoma |
| E_03513 | chr20:48900221-48901229 | Liver | hepatocellular carcinoma cell | hepatocellular carcinoma |
Expression of Target Genes for the Enhancer