About Enhancer
| Enhancer ID: | E_03503 |
| Species: | Mus musculus |
| Position : | chr15:63648126-63648667   |
| Year: | 2018 |
| Title: | A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 29342133 |
| Tissue: | bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | primary mouse HSC/progenitors |
| Cell Type: | hematopoietic stem cell |
| Cell Ontology ID: | CL:0000037 |
| Experiment Type: | In-vivo enhancer-module deletion; HSC functional analysis |
| High Throughput Method: | ATAC-seq; H3K27ac/TF ChIP-seq; human AML accessibility analysis |
| Low Throughput Method: | BENC-C deletion; Myc expression; flow cytometry; transplantation |
About Target Gene
| Target gene : | Myc |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03538 | chr15:63611116-63736746 | bone marrow | leukemic hematopoietic stem/progenitor cell | acute myeloid leukemia |
Expression of Target Genes for the Enhancer