About Enhancer
| Enhancer ID: | E_03557 |
| Species: | Mus musculus |
| Position : | chr15:63714919-63952099   |
| Year: | 2018 |
| Title: | A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. |
| Genome Build: | mm10 |
| Enhancer Type: | Super-enhancer |
| Condition: | Disease |
| Disease Name: | Leukaemia |
| PMID: | 29342133 |
| Tissue: | blood / hematopoietic system |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Bone Marrow |
| Experiment Type: | TF-binding/chromatin assay; Disease-associated enhancer analysis |
| High Throughput Method: | ChIP-seq; ATAC-seq |
| Low Throughput Method: | ChIP-qPCR/ChIP; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Myc |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
8 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03538 | chr15:63611116-63736746 | bone marrow | leukemic hematopoietic stem/progenitor cell | acute myeloid leukemia |
| E_03441 | chr15:63736276-63736746 | bone marrow | hematopoietic stem cell | NA |
| E_03969 | chr15:63833002-63863200 | colon | malignant cell | Colon Cancer |
| E_03970 | chr15:63833002-63863200 | colon | malignant cell | Colon Cancer |
| E_03993 | chr15:63865799-63896492 | colon | malignant cell | Colon Cancer |
| E_03994 | chr15:63865799-63896492 | colon | malignant cell | Colon Cancer |
| E_03995 | chr15:63894512-63932136 | colon | malignant cell | Colon Cancer |
| E_03996 | chr15:63894512-63932136 | colon | malignant cell | Colon Cancer |
Expression of Target Genes for the Enhancer