About Enhancer
| Enhancer ID: | E_03564 |
| Species: | Homo sapiens |
| Position : | chr10:35949193-35950411   |
| Year: | 2025 |
| Title: | A human-specific enhancer fine-tunes radial glia potency and corticogenesis. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 40369080 |
| Tissue: | cerebral cortex |
| Tissue Ontology ID: | UBERON:0000956 |
| Cell Type: | radial glial cell |
| Cell Ontology ID: | CL:0000681 |
| Experiment Type: | in vivo reporter assay; genome editing; Endogenous enhancer perturbation; Disease-variant functional analysis; In vivo functional validation |
| High Throughput Method: | RNA-seq; scRNA-seq; ChIP-qPCR; CRISPRi; single-cell RNA-seq |
| Low Throughput Method: | Immunohistochemistry; luciferase reporter assay; RT-qPCR; Mouse genetic deletion/knock-in; In vivo phenotyping |
About Target Gene
| Target gene : | FZD8 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer