About Enhancer
| Enhancer ID: | E_03575 |
| Species: | Mus musculus |
| Position : | chr5:135012000-135012856   |
| Year: | 2019 |
| Title: | Lmx1a drives Cux2 expression in the cortical hem through activation of a conserved intronic enhancer. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 30770393 |
| Tissue: | forebrain |
| Tissue Ontology ID: | UBERON:0001890 |
| Cell Source: | Embryonic neural progenitor |
| Cell Type: | neural progenitor cell |
| Cell Ontology ID: | CL:0011020 |
| Experiment Type: | Enhancer activity assay, TF binding assay; In vivo functional validation |
| Low Throughput Method: | Transgenic Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR; In vivo phenotyping |
About Target Gene
| Target gene : | Cux2 |
About TF
| TF name : | Lmx1a |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Lmx1a | Hs_Dopaminergic_Neurogenesis_WP2855_87239 | wikipathways | 19 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer