Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03581
Species: Mus musculus
Position : chr8:87424785-87425735
Year: 2015
Title: The DEK Oncoprotein Is a Critical Component of the EKLF/KLF1 Enhancer in Erythroid Cells.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  26303528
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: Mouse erythroid progenitor cells
Cell Type: erythroid progenitor cell
Cell Ontology ID: CL:0000038
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: RNA-seq
Low Throughput Method: ChIP-RT-qPCR, CRISPR Knockout, shRNA knockdown, RT-RT-qPCR, Western blot, EMSA, Transgenic Reporter Assay
About Target Gene
Target gene : Klf1
About TF
TF name : Dek
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Dek B-WICH complex positively regulates rRNA expression reactome 89
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer