About Enhancer
| Enhancer ID: | E_03582 |
| Species: | Mus musculus |
| Position : | chr3:34563695-34565695   |
| Year: | 2011 |
| Title: | Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 21331042 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Axial Stem Cell |
| Experiment Type: | TF-binding/chromatin assay; Chromatin interaction assay; In vivo functional validation |
| Low Throughput Method: | EMSA/gel-shift assay; Transgenic/LacZ assay |
About Target Gene
| Target gene : | Sox2 |
About TF
| TF name : | Tbx6 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Tbx6 | Hs_Gene_regulatory_network_modelling_somitogenesis_WP2854_87527 | wikipathways | 12 |
| Tbx6 | Hs_Mesodermal_Commitment_Pathway_WP2857_87780 | wikipathways | 47 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer