About Enhancer
| Enhancer ID: | E_03613 |
| Species: | Homo sapiens |
| Position : | chr13:48974891-48975426   |
| Year: | 2025 |
| Title: | Increasing RB1 Expression by Targeting EZH2 in Triple-Negative Breast Cancer. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | triple-negative breast carcinoma |
| PMID: | 40070134 |
| MONDO: | MONDO:0005494 |
| Tissue: | breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | HCC1806 |
| CVCL ID: | CVCL_1258 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer functional perturbation assay |
| High Throughput Method: | ATAC-seq |
| Low Throughput Method: | CRISPR-Cas9 enhancer knockout; RT-qPCR; Western blot; ChIP-qPCR; qPCR |
About Target Gene
| Target gene : | RB1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer