About Enhancer
| Enhancer ID: | E_03625 |
| Species: | Homo sapiens |
| Position : | chr4:70849125-70849971   |
| Year: | 2019 |
| Title: | Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | salivary gland acinic cell carcinoma |
| PMID: | 30664630 |
| MONDO: | MONDO:0006400 |
| Tissue: | saliva-secreting gland |
| Tissue Ontology ID: | UBERON:0001044 |
| Cell Source: | AciCC primary tumor cells |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq; RNA-seq; Hi-C; WGS |
| Low Throughput Method: | Luciferase Reporter Assay; FISH; RT-RT-qPCR; Western blot |
About Target Gene
| Target gene : | NR4A3 |
About TF
| TF name : | NR4A3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NR4A3 | Nuclear Receptor transcription pathway | reactome | 51 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer