Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03632
Species: Homo sapiens
Position : chr11:5305481-5306682
Year: 2011
Title: Cohesin mediates chromatin interactions that regulate mammalian 汕-globin expression.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  21454523
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: K-562
CVCL ID: CVCL_0004
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Chromatin interaction assay; Functional perturbation assay
Low Throughput Method: 3C; RAD21/SMC1/NIPBL/CTCF ChIP-qPCR; RAD21 ChIP-loop; SMC1 knockdown; CTCF knockdown; RT-qPCR; Western blot
About Target Gene
Target gene : HBG2
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 4 found
Enhancer ID Position Tissue Cell Disease
E_02356 chr11:5222500-5323700 blood erythroid cell NA
E_02363 chr11:5222500-5323700 blood erythroid cell NA
E_02364 chr11:5222500-5323700 blood erythroid cell NA
E_02365 chr11:5222500-5323700 blood erythroid cell NA
Expression of Target Genes for the Enhancer