About Enhancer
| Enhancer ID: | E_03634 |
| Species: | Homo sapiens |
| Position : | chr8:128647663-128667652   |
| Year: | 2016 |
| Title: | Active medulloblastoma enhancers reveal subgroup-specific cellular origins. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Medulloblastoma |
| PMID: | 26814967 |
| MONDO: | MONDO:0007959 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Primary Medulloblastoma Tissue |
| Cell Type: | medulloblastoma cell |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq; RNA-seq; DNA methylation profiling |
| Low Throughput Method: | Transgenic Reporter Assay; ChIP-RT-qPCR; RT-RT-qPCR |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | HLX |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| HLX | IL12-mediated signaling events | pid | 62 |
| HLX | Hs_TYROBP_Causal_Network_WP3945_90843 | wikipathways | 54 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer