Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03635
Species: Homo sapiens
Position : chr8:128647663-128667652
Year: 2016
Title: Active medulloblastoma enhancers reveal subgroup-specific cellular origins.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: Medulloblastoma
PMID:  26814967
MONDO: MONDO:0007959
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: Primary Medulloblastoma Tissue
Cell Type: medulloblastoma cell
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay
High Throughput Method: ChIP-seq; RNA-seq; DNA methylation profiling
Low Throughput Method: Transgenic Reporter Assay; ChIP-RT-qPCR; RT-RT-qPCR
About Target Gene
Target gene : MYC
About TF
TF name : LHX2
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_03634 chr8:128647663-128667652 brain medulloblastoma cell Medulloblastoma
E_03636 chr8:128647663-128667652 brain medulloblastoma cell Medulloblastoma
Expression of Target Genes for the Enhancer