About Enhancer
| Enhancer ID: | E_03655 |
| Species: | Homo sapiens |
| Position : | chr11:69329695-69333028   |
| Year: | 2017 |
| Title: | Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 28777932 |
| MONDO: | MONDO:0004989 |
| Tissue: | pleural effusion |
| Tissue Ontology ID: | UBERON:0000175 |
| Cell Source: | MCF-7 DR-GFP |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Functional perturbation assay |
| High Throughput Method: | RNA CaptureSeq; RNA-seq |
| Low Throughput Method: | CRISPR interference (dCas9-KRAB); RT-qPCR |
About Target Gene
| Target gene : | CCND1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02524 | chr11:69329684-69330954 | breast | malignant cell | Breast Cancer |
| E_02525 | chr11:69329684-69330954 | breast | malignant cell | Breast Cancer |
| E_02541 | chr11:69329684-69330954 | colon | malignant cell | NA |
| E_03628 | chr11:69329695-69333028 | pleural effusion | malignant cell | breast carcinoma |
| E_03629 | chr11:69329695-69333028 | pleural effusion | malignant cell | breast carcinoma |
Expression of Target Genes for the Enhancer