About Enhancer
| Enhancer ID: | E_03688 |
| Species: | Homo sapiens |
| Position : | chr5:131406243-131406930   |
| Year: | 1993 |
| Title: | The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 8460159 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Jurkat |
| CVCL ID: | CVCL_0065 |
| Cell Type: | T cell |
| Cell Ontology ID: | CL:0000084 |
| Experiment Type: | Enhancer activity assay; TF binding assay; Chromatin accessibility assay; Cis-regulatory mapping |
| Low Throughput Method: | DNase I hypersensitivity assay; enhancer deletion mapping; restriction mapping; transient transfection; CAT reporter assay; PMA/A23187 stimulation; cyclosporin A inhibition; EMSA; competition EMSA |
About Target Gene
| Target gene : | IL3 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
8 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02035 | chr5:131406243-131406930 | blood | T cell | NA |
| E_02036 | chr5:131406243-131406930 | blood | T cell | NA |
| E_02037 | chr5:131406243-131406930 | blood | T cell | NA |
| E_02038 | chr5:131406243-131406930 | blood | T cell | NA |
| E_03687 | chr5:131406243-131406930 | blood | T cell | NA |
| E_04044 | chr5:131406243-131406930 | blood | T cell | NA |
| E_04598 | chr5:131406243-131406930 | blood | T cell | NA |
| E_04599 | chr5:131406243-131406930 | blood | T cell | NA |
Expression of Target Genes for the Enhancer