Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03744
Species: Homo sapiens
Position : chr8:128482317-128483854
Year: 2009
Title: The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Genome Build: hg18
Enhancer Type: Enhancer
Condition: Disease
Disease Name: colorectal cancer
PMID:  19561607
MONDO: MONDO:0005575
Tissue: ascitic fluid
Tissue Ontology ID: UBERON:0007795
Cell Source: COLO 205
CVCL ID: CVCL_0218
Cell Type: epithelial cell of colon
Experiment Type: Enhancer activity assay; Chromatin interaction assay; Allele-specific regulatory assay; Enhancer chromatin-state assay
High Throughput Method: NimbleGen 8q24 high-density tiling array
Low Throughput Method: Luciferase reporter assay; allele-specific reporter assay; p300 ChIP-qPCR; H3K4me1 ChIP-qPCR; H3K4me3 ChIP-qPCR; RNA polymerase II ChIP-qPCR; 3C; competitive PCR
About Target Gene
Target gene : MYC
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg18) 3 found
Enhancer ID Position Tissue Cell Disease
E_03742 chr8:128482317-128483854 colon malignant cell colorectal cancer
E_03747 chr8:128482317-128483854 colon epithelial cell of colon colorectal cancer
E_04630 chr8:128482317-128483854 prostate gland malignant cell prostate cancer
Expression of Target Genes for the Enhancer