About Enhancer
| Enhancer ID: | E_03811 |
| Species: | Homo sapiens |
| Position : | chr2:223164846-223165065   |
| Year: | 2016 |
| Title: | FOXD3 Promotes PAX3 Expression in Melanoma Cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Melanoma |
| PMID: | 26252164 |
| MONDO: | MONDO:0005105 |
| Tissue: | skin |
| Tissue Ontology ID: | UBERON:0002097 |
| Cell Source: | Melanoma |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Disease-associated enhancer analysis |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; EMSA/gel-shift assay |
About Target Gene
| Target gene : | PAX3 |
About TF
| TF name : | FOXD3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOXD3 | POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | reactome | 13 |
| FOXD3 | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer