About Enhancer
| Enhancer ID: | E_03812 |
| Species: | Homo sapiens |
| Position : | chr2:223164458-223164688   |
| Year: | 2016 |
| Title: | FOXD3 Promotes PAX3 Expression in Melanoma Cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | cutaneous melanoma |
| PMID: | 26252164 |
| MONDO: | MONDO:0005012 |
| Tissue: | zone of skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | A-375 |
| CVCL ID: | CVCL_0132 |
| Cell Type: | melanoma cell |
| Experiment Type: | Enhancer activity assay |
| Low Throughput Method: | Luciferase Reporter Assay; EMSA |
About Target Gene
| Target gene : | PAX3 |
About TF
| TF name : | FOXD3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOXD3 | POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | reactome | 13 |
| FOXD3 | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer