About Enhancer
| Enhancer ID: | E_03824 |
| Species: | Mus musculus |
| Position : | chr1:133347574-133364574   |
| Year: | 2018 |
| Title: | Homeostatic Response of Mouse renin Gene Transcription in a Hypertensive Environment Is Mediated by a Novel 5' Enhancer. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Hypertension |
| PMID: | 29358217 |
| Cell Source: | As4.1,Tsukuba hypertensive mice |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Endogenous enhancer perturbation; In vivo functional validation; Disease-associated enhancer analysis |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Ren1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer